Immerse yourself in history as you stroll through beautifully preserved medieval towns and a stunning imperial palace. Sample the fruits of the Rhine’s famously excellent wineries and enjoy traditional treats as you follow your local guides through the destinations they call home. And, to fully appreciate the lush environment of this verdant river valley, we’ll give you several opportunities to get active out in nature—such as a canoe ride through the Mainschleife nature reserve.

The Rhine also gives us access to such remarkable destinations as the Alsatian capital of Strasbourg or the multicultural city of Basel in Switzerland. And not too far from Basel lies a destination every world traveler should visit at least once, the scenic, lakeside city of Zurich. We’ll spend two nights here in five-star luxury at The Dolder Grand Hotel, expanding our journey on land to embrace Swiss cultural highlights in the country’s largest city.